{"id":280304,"date":"2020-10-09T13:18:58","date_gmt":"2020-10-09T03:18:58","guid":{"rendered":"https:\/\/southburnett.com.au\/news2\/?p=280304"},"modified":"2020-10-09T13:21:40","modified_gmt":"2020-10-09T03:21:40","slug":"vaccines-will-target-later-strains","status":"publish","type":"post","link":"https:\/\/southburnett.com.au\/news2\/2020\/10\/09\/vaccines-will-target-later-strains\/","title":{"rendered":"Vaccines Will Target Later Strains"},"content":{"rendered":"
\"\"<\/a>
Biomolecular modelling of the COVID-19 spike protein (Graphic: CSIRO)<\/figcaption><\/figure>\n

October 9, 2020<\/strong><\/p>\n

CSIRO researchers have shared some good news about\u00a0SARS-CoV-2, the virus that causes COVID-19.<\/p>\n

Their research has shown potential vaccines should not be affected by how the virus has changed since it was first detected.<\/p>\n

A CSIRO spokesperson said most vaccines under development around the world have been modelled on the original “D-strain” of the virus, which was more common early in the pandemic.<\/p>\n

Since then, the virus has evolved into the “G-strain” which is now more dominant around the world and makes up about 85 per cent of SARS-CoV-2 genomes published.<\/strong><\/p>\n

There had been fears the G-strain, or the “D614G mutation” within the main protein on the surface of the virus, could have a negative affect on vaccines under development.<\/p>\n

However researchers have found no evidence the change will adversely impact the efficacy of potential vaccines.<\/p>\n

And it means that – unlike the flu, which requires yearly vaccinations as the virus changes – a vaccine against\u00a0SARS-CoV-2 should provide longer protection.<\/p>\n

CSIRO chief executive Dr Larry Marshall said the research was critically important in the race to develop a vaccine.<\/p>\n

\u201cThis brings the world one step closer to a safe and effective vaccine to protect people and save lives,\u201d Dr Marshall said.<\/strong><\/p>\n

“Research like this, at speed, is only possible through deep collaboration with partners both in Australia and around the world.<\/p>\n

\u201cWe are tackling these challenges head-on together and delivering real world solutions from world-leading Australian science.\u201d<\/p>\n

CSIRO\u2019s Dangerous Pathogens team leader Dr S.S. Vasan said most potential COVID-19 vaccines were targeting the virus\u2019 “spike protein” as this binds to receptors in the lungs and airways,\u00a0 the entry point to infect cells.<\/p>\n

\u201cDespite this D614G mutation to the spike protein, we confirmed through experiments and modelling that vaccine candidates are still effective,” Dr Vasan said.<\/p>\n

\u201cWe\u2019ve also found the G-strain is unlikely to require frequent \u2018vaccine matching\u2019, where new vaccines need to be developed seasonally to combat the virus strains in circulation, as is the case with influenza.\u201d<\/p>\n

CSIRO recently concluded pre-clinical studies for two potential vaccines – from Inovio Pharmaceuticals and the University of Oxford – with peer-reviewed reports to be published in coming months.<\/p>\n

\"\"<\/a>
(Graphic: CSIRO)<\/figcaption><\/figure>\n","protected":false},"excerpt":{"rendered":"

CSIRO researchers have shared some good news about\u00a0SARS-CoV-2, the virus that causes COVID-19.<\/p>\n","protected":false},"author":20,"featured_media":280313,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[1455,172,3],"tags":[],"yoast_head":"\nVaccines Will Target Later Strains - southburnett.com.au<\/title>\n<meta name=\"description\" content=\"CSIRO researchers have shared some good news about\u00a0SARS-CoV-2, the virus that causes COVID-19.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/southburnett.com.au\/news2\/2020\/10\/09\/vaccines-will-target-later-strains\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Vaccines Will Target Later Strains - southburnett.com.au\" \/>\n<meta property=\"og:description\" content=\"CSIRO researchers have shared some good news about\u00a0SARS-CoV-2, the virus that causes COVID-19.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/southburnett.com.au\/news2\/2020\/10\/09\/vaccines-will-target-later-strains\/\" \/>\n<meta property=\"og:site_name\" content=\"southburnett.com.au\" \/>\n<meta property=\"article:published_time\" content=\"2020-10-09T03:18:58+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2020-10-09T03:21:40+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/southburnett.com.au\/news2\/wp-content\/uploads\/2020\/10\/20201009covid3.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"300\" \/>\n\t<meta property=\"og:image:height\" content=\"200\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Anne Miller\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Anne Miller\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"2 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/southburnett.com.au\/news2\/2020\/10\/09\/vaccines-will-target-later-strains\/\",\"url\":\"https:\/\/southburnett.com.au\/news2\/2020\/10\/09\/vaccines-will-target-later-strains\/\",\"name\":\"Vaccines Will Target Later Strains - 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